Follow-up of ovarian function post-chemotherapy following ovarian cryopreservation and transplantation

Ovarian cancer treatment: the benefit of patient telephone follow-up post-chemotherapy.

Approximately 2,500 women in Canada were diagnosed with cancer of the ovary in 1997 (NCIC, 1997). Standard therapy consists of surgical tumour debulking and cytotoxic chemotherapy. Very little data are available examining the most appropriate outpatient management of patients receiving chemotherapy. The objective of this study was to assess the impact of and benefit received from telephone foll...

Staging and Follow-up of Ovarian Cancer

Safety of Ovarian Cryopreservation and Transplantation in Nude Mice Bearing Human Epithelial Ovarian Cancer

The treatments of ovarian cancer mainly include surgery and chemotherapy. After surgery, patients will lose ovarian function permanently. A considerable portion of patients with epithelial ovarian cancer are women of childbearing age. The loss of ovarian function will lead to a serial of clinical symptoms or metabolic syndrome (Michelsen et al., 2009). The patients’ quality of life suffers seve...

Ovarian function 6 years after cryopreservation and transplantation of whole sheep ovaries.

Whole ovary cryopreservation and transplantation has been proposed as a method for preserving long-term ovarian function. This work reports ovarian function 6years post transplantation of frozen-thawed whole sheep ovaries. Three 9-month-old Assaf sheep underwent unilateral oophorectomy to provide organs for the experiments. After perfusing with cold University of Wisconsin solution supplemented...

Ovarian function and ovarian blood supply following premenopausal abdominal hysterectomy

INTRODUCTION The issue of conserving the ovaries at hysterectomy in premenopausal women with benign gynecologic disease has been the subject of considerable controversy. Some clinicians prefer prophylactic oophorectomy in premenopausal women during hysterectomy to prevent future development of malignant changes in conserved ovaries. Other clinicians prefer to conserve apparently normal ovaries,...